William Harper
I am an endocrinologist, general internist and Associate Professor of Medicine at McMaster University and staff physician at Hamilton health Sciences since 2002. My clinical practice has included diabetes, endocrinology, general medicine and medical assistance in dying (MAiD). I have been involved in undergraduate and postgraduate medical education, clinical research trials, clinical guideline development, medical licensing adjudication, as well as university and hospital administration. My primary motivation in all these endeavors has been to focus on decision-making through uncertainty both in the clinical realm as well as in organizational structures. My interests include applying convexity and game theoretical equilibrium strategies to problems with existential risk.
My CV
Educational Background
Degrees
Doctor of Medicine. University of Toronto, Department of Medicine, Toronto, Ontario, Canada. 1996.
Bachelor of Science, Chemistry. University of Toronto, Department of Chemistry, Toronto, Ontario, Canada. 1992.
Fellowships & Residency Training
Molecular Endocrinology. University of Toronto, Department of Medicine, Toronto, Ontario, Canada. 2002.
Endocrinology & Metabolism. University of Toronto, Department of Medicine, Toronto, Ontario, Canada. 2001.
Fellow (FRCPC), Division of Medicine. Royal College of Physicians and Surgeons of Canada, Canada. 2000.
Internal Medicine. University of Toronto, Department of Medicine, Toronto, Ontario, Canada. 1999.
Certifications
Endocrinology & Metabolism, Certificate of Special Competence. Royal College of Physicians and Surgeons of Canada, Canada. 2001.
License for Independent Medical Practice. College of Physicians and Surgeons of Ontario, Canada. 2000.
Internal Medicine, Specialist Certificate. Royal College of Physicians and Surgeons of Canada, Canada. 2000.
Internal Medicine, Certified Diplomate. American Board of Internal Medicine, USA. 1999.
Licentiate, Medical Council of Canada Qualifying Examination (MCCQE). Medical Council of Canada, Ottawa, Canada. 1998.
United States Medical Licensing Examination (USMLE). The Federation of State Medical Boards of the U.S., Inc. Euless, TX, USA. Step 3: 1997, Step 2: 1996, Step 1: 1994.
Certificates
ACS101: Introduction to Complexity and Applied Complexity. Applied Complexity Science, LLC. Twice weekly 1.5h classes (26 classes) from Jan 13-April 8 2021.
13th Real World Risk Management. The Real World Risk Institute LLC. Lebanese American University, New York, USA. February 2020.
Faculty of Health Sciences Academic Leadership Program, 2012-2013 Inaugural. McMaster University, June 5, 2013.
Leadership Development Program for Directors & Physician Leaders.
St. Joseph’s Healthcare Hamilton in partnership with The DeGroote School of Business Executive Education, McMaster University. November 23, 2012.
Current Status at McMaster University
Associate Professor, Department of Medicine.
Divisions of Endocrinology and General Internal Medicine.
Professional Organizations
Canadian Association for Medical Education
Canadian Diabetes Association
Canadian Society of Endocrinology & Metabolism
Ontario Medical Association
Canadian Medical Association
Endocrine Society
Alpha Omega Alpha Honor Medical Society
Employment History
Active Staff, Department of Medicine.
Hamilton Health Sciences, Hamilton ON.
May 2002 – Present.
Clinician-Educator, Associate Professor, Department of Medicine.
McMaster University, Hamilton ON.
July 2007 – Present.
Clinician-Educator, Assistant Professor, Department of Medicine.
McMaster University, Hamilton ON.
May 2002 – June 2007.
Clinician-Investigator Trainee.
University of Toronto, Toronto ON.
July 2000 – February 2002.
Endocrinology & Metabolism Postgraduate Year 4 Trainee.
University of Toronto, Toronto ON.
July 1999 – June 2000.
Internal Medicine Postgraduate Year 1-3 Trainee.
University of Toronto, Toronto ON.
July 1996 – June 1999.
Scholarly & Professional Activities
Education
Member, Internal Medicine Examination Board, Royal College of Physicians and Surgeons of Canada. June 2012 – Present.
Editorial Boards
Dissemination and Implementation (D&I) Committee Member, Canadian Diabetes Association Clinical Practice Guideline for the Prevention and Management of Diabetes in Canada, 2013 Revision.
March 2012 – 2015.
Executive Committee Member, Canadian Diabetes Association Clinical Practice Guideline for the Prevention and Management of Diabetes in Canada, 2013 Revision.
August 2010 – 2015.
Working Group Committee Member, Canadian Diabetes Association Clinical Practice Guideline for the Prevention and Management of Diabetes in Canada, 2008 Revision. Working Groups for sections on Pharmacological Management of Type 2 Diabetes and Erectile Dysfunction.
February 2006 – September 2008.
Expert Advisor Steering Committee Member, Canadian Diabetes Association Clinical Practice Guideline for the Prevention and Management of Diabetes in Canada, 2008 Revision.
July 2005 – September 2008.
Website Editor, Website for the Division of Endocrinology & Metabolism, Department of Medicine, McMaster University, Hamilton ON.
2004 – Present.
Website Editor, www.drharper.ca
Sept 2003 – Present.
Editor-in-Chief, Knowing Diabetes, quarterly newsletter for Diabetes Hamilton, a local advocacy group for close to 2000 people in the greater Hamilton area and 650 of their health care providers.
Jan 2003 – Aug 2011.
Journal Referee
Amirthavasar G, et al. The landscape of diabetes education in Ontario: A descriptive overview. Canadian Journal of Diabetes. June 2012.
Duarte H, et al. Clinical evaluation of De Marco Formula as an adjunctive therapy for infected ischemic diabetic foot: A prospective randomized controlled trial. Canadian Journal of Clinical Pharmacology. June 2008.
Chung D, Radomski SB. Diagnosis and Management of Erectile Dysfunction in Diabetic Men: A Review. Canadian Journal of Diabetes. May 2006.
Expert External Reviewer. Canadian Diabetes Association 2003 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada. Reviewed six sections (1, 2, 8, 12, 19, 24). Canadian Journal of Diabetes 2003; 27(suppl 2):S1-S152.
Research
Clinical Trial Research Activity
Coinvestigator and Local PI (West Lincoln HHS Site). ACTCOVID19 Trial. Hamilton, PHRI. 2020-2022
Local PI and Coinvestigator for this randomized clinical trial.
Coinvestigator. REMIT-iGLARLixi Trial. Hamilton Site. 2017-2020
Local coinvestigator for this multicenter randomized clinical trial.
Principal Investigator, ORIGINALE Study, Hamilton site. 2012 – 2015
Local principle investigator for the Hamilton General Hospital site of this multicentre international randomized clinical trial.
Principle Investigator, MRTSH01505 Study. 2008 – 2011
Local principle investigator for the HGH site of this multi-centre Phase II clinical trial.
Coinvestigator, SR121463B (V2-R Antagonist) Study. 2006
Local study investigator for Hamilton General Hospital site of this multicentre phase 2 clinical trial.
Coinvestigator, APPROACH Study. 2005
Local coinvestigator for this phase 2 clinical trial.
Events adjudicator, ORIGIN Study. 2004 – 2012
Responsible for adjudication of all diabetes microvascular outcomes in this multicentre international randomized clinical trial.
Coinvestigator, VICTORY Study. 2004
Local coinvestigator for this phase 2 clinical trial.
Principal Investigator, ORIGIN Erectile Dysfunction Substudy. 2003 – 2012.
Principle investigator of this ORIGIN substudy.
Study Investigator, ACCORD Study. 2002 – 2010
Local study investigator for the Hamilton site of this multicentre international randomized clinical trial.
Principal Investigator, ORIGIN Study, Hamilton site. 2002 – 2012
Local principle investigator for the Hamilton General Hospital site of this multicentre international randomized clinical trial.
Clinical-Advisor, STREAM Study. 2002 – 2005.
Diabetes consultant for Hamilton site of this multicentre randomized clinical trial.
Areas of Interest
Research
Game Theory
Decisions in Uncertainty
Diversity, Equity and Inclusion (DEI)
Diabetes mellitus inpatient management
Diabetes mellitus and cardiovascular disease
Diabetes mellitus and erectile dysfunction
Thyroid Disorders
Neuroendocrine tumors
Sodium Disorders
Cardiac Syncope
Teaching
Conflict management in medical education
Postgraduate medical education: internal medicine, endocrinology & metabolism
Undergraduate medical education: tutoring, lecturing, curriculum development, faculty development
Clinical
Diabetes mellitus: outpatient and inpatient management
Diabetes mellitus: organization of care
Thyroid multinodular disease and differentiated thyroid cancer
Pituitary Disease
Neuroendocrine tumors
Honours and Awards
Certificate of Merit for Teaching Excellence, Core Internal Medicine Clerkship, McMaster University, 2015.
Department of Medicine Teaching Award, Undergraduate Studies, 2011.
Dr. Ari Shali Teaching Award, Michael DeGroote School Medicine, 2011.
Certificate of Merit Award for Teaching Excellence, McMaster, 2008-10.
General Internist Clinical Teaching Award, McMaster, 2010.
Certificate of Merit Award, Canadian Association for Medical Education, 2008.
Pre-clerkship Excellence in Tutorial Education Award, McMaster, 2006.
General Internist Clinical Teaching Award, McMaster, 2005.
General Internist Clinical Teaching Award, McMaster, 2003.
Clinical-Scientist Training Program Award, University of Toronto, 2000-2002.
Research Fellowship, Medical Research Council of Canada, 2000-2002.
Institute of Medical Science Merit Award, University of Toronto, 2000.
William S. Fenwick Fellowship, University of Toronto, 2000.
Graham Campbell Fellowship, University of Toronto, 2000.
Edward Christie Stevens Fellowship in Medicine, University of Toronto, 2000.
Sopman Humanitarian Award, University Health Network, Toronto, 1999.
Geriatric Medicine Award, Sunnybrook Health Science Centre, Toronto, 1999.
Walter F. Watkins Scholarship, University of Toronto, 1993-1994.
Lawrence V. Redman Prize in Chemistry, University of Toronto, 1990.
University of Toronto Erindale College In-Course Scholarship, 1990.
University of Toronto Erindale College Admission Scholarship, 1989.
Courses Taught
Lecturer, Medical Foundations 2. MF2 Introductory Lecture, Thyroid Disorders Lecture, Endocrine CPC Lecture. Michael G. DeGroote School of Medicine, McMaster University.
2006 – 2012
Tutor, Unit 5. Michael G. DeGroote School of Medicine, McMaster University.
7 undergraduate medical students/year (approx)
2004 – 2005
Lecturer, Unit 3. Thyroid Disorders Lecture. Michael G. DeGroote School of Medicine, McMaster University.
2003 – 2005
Tutor, Unit 3. Michael G. DeGroote School of Medicine, McMaster University.
6 undergraduate medical students/year
2003 – 2005
Clinical Skills Instructor, Clinical Teaching Unit, Hamilton General Hospital, Postgraduate medical education, McMaster University.
Bedside physical exam sessions (1 hour approx): 7 sessions/year
Lecturer, Postgraduate medical education and Michael G. DeGroote School of Medicine, McMaster University.
Lectures (1 hour approx) on various endocrine topics: 18 lectures/year (approx)
2002 – Present
Clinical Supervisor, Internal Medicine, Clinical Teaching Unit, Hamilton General Hospital, Postgraduate medical education and Michael G. DeGroote School of Medicine, McMaster University.
Number students supervised (approx): undergraduate medical students 12/year, postgraduate medical trainees 14/year.
2002 – Present
Clinical Supervisor, Endocrinology, Postgraduate medical education and Michael G. DeGroote School of Medicine, McMaster University.
Number students supervised (approx): undergraduate medical students 17/year, postgraduate medical trainees 23/year.
2002 – Present
Lecturer, Evidence-Based Medicine Diabetes Symposium, Division of Endocrinology, McMaster University.
1 hour lecture during half-day symposium, Continuing Medical Education.
2004 – 2005
Lecturer, Endocrinology, McMaster Muskoka Seminars, Department of Psychiatry, McMaster University.
1 week of half-day seminars, Continuing Medical Education.
2003 – 2004 (7th and 8th Annual McMaster Muskoka Seminars)
Supervisorships
Undergrad MD Student. Learning Assistance Tutor. MD Undergraduate Program, McMaster. November 2018 - 2020.
College of Physicians & Surgeons of Ontario (CPSO) Registration Pathway 4
Dr. Sara Ahmed, General Internist, West Lincoln Memorial Hospital (HHS)
July 2019 – January 2021
Dr. Azar Sadeghalvad, General Internist, West Lincoln Memorial Hospital (HHS)
June 2018 – February 2019
Undergrad MD Student. Professionalism and Organizational Remediation Coach
MD Undergraduate Program, McMaster. May – August 2018.
Research Project Supervisor, Thyroid Storm Study.
Postgraduate medical residents: Jackie Ostro, Alex Inman. 2011-2012.
Research Project Supervisor, Diabetes-related worry in Type 1 Diabetes mellitus.
Postgraduate student: Michael Coons. 2009-2011.
Research Project Supervisor, Thyroid Cancer Quality Insurance Project.
Postgraduate medical resident: Ujjaini Sarkar. 2009-2010.
Case Report Supervisor, PTU-associated Vasculitis Case.
Postgraduate medical resident: Rebecca Amer. 2005-2006.
Research Project Supervisor, Surgical Site Infection Prophylaxis Project
Postgraduate surgical resident: Shawn Forbes. 2005-2008.
Case Report Supervisor, Thyrotropinoma Case.
Postgraduate medical resident: Eva Kogan. 2005-2006.
Case Report Co-Supervisor, Post-transphenoidal surgery meningitis Case.
Postgraduate medical resident: Blair Leonard. 2005-2006.
Research Project Supervisor, Pancreatic Cancer & Diabetes Study
Postgraduate surgical resident: William Harris. 2004.
Case Report Supervisor, Insulinoma – Seminoma Case.
Postgraduate medical resident: Tim O’Shea. 2004 – 2005.
Research Project Supervisor, Cardiac Syncope Study.
Postgraduate medical resident: Rajesh Hiralal. 2004 – 2005.
Research Project Supervisor, Diabetes Quality Assurance Project.
Postgraduate medical resident: Vikas Khera. 2003 – 2005.
Research Funding
Postdoctoral Fellowship, Canadian Institutes of Health Research.
Place of Tenure: Institute of Medical Sciences, University of Toronto.
Stipend: $48,500/per annum. July 2000 – February 2002.
Lifetime Publications
Peer-Reviewed Publications
Journal Articles
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Eikelboom J, Jolly S, Belley-Cote E, Whitlock R, Rangarajan S, Xu L, Heena L, Bangdiwala S, Tarhuni W, Hassany M, Kontsevaya A, Harper W, et al. Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomized, controlled trial. The Lancet Respiratory Medicine 10:1160-1168, 2022
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Eikelboom J, Jolly S, Belley-Cote E, Whitlock R, Rangarajan S, Xu L, Heena L, Bangdiwala S, Luz Diaz M, Diaz R, Yusufali A, Kumar Sharma S, Tarhuni W, Hassany M, Harper W, et al. Colchicine and the combination of rivaroxaban and aspirin in patients hospitalized with COVID-19 (ACT): an open-label, factorial, randomized, controlled trial. The Lancet Respiratory Medicine 10:1169-1177, 2022.
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Frolic A, Miller P, Harper W, Oliphant A. MAiD to Last: Creating a Care Ecology for Sustainable Medical Assistance in Dying Services. HealthCare Ethics Committee (HEC) Forum 34:409-428, 2022.
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Eikelboom J, Rangarajan S, Jolly S, Belley-Cote E, Whitlock R, Beresh H, Lewis G, Xu L, Chan N, Bangdiwala S, Diaz R, Orlandini A, Hassany M, Tarhuni W, Yusufali A, Sharma S, Kontsevaya A, Lopez-Jaramillo P, Avezum A, Dans A, Wasserman S, Felix C Kazmi K, Pais P, Xavier D, Lopes R, Berwanger O, Nkeshimana M, Harper W, et al. The Anti-Coronavirus Therapies (ACT) Trials: Design, Baseline Characteristics, and Challenges. CJC OPEN 4:568-576, 2022.
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Harper W, Buren Y, Ariaeinejad A, Crowther M, Anand S. Equity and Game-Theory strategies to promote gender diversity and inclusion in an Academic Health Science Centre. CJC Open 3 (12, Suppl):S54-S61 2021.
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Goldenberg R, Clement M, Hanna A, Harper W, et al. Pharmacologic Management of Type 2 Diabetes: 2016 Interim Update. Can J Diabetes 40:193-95, 2016.
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Fast S, Hegedus L, Pacini F, Harper W, et al. Long-term efficacy of modified-release recombinant human thyrotropin augmented radioiodine therapy for benign multinodular goiter: results from a multicenter, international, randomized, placebo-controlled, dose-selection study. Thyroid 24(4):727-35, 2014.
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King, L, Gardhouse A, Harper W. Atypical presentation of acute encephalomyelitis associated with hyperosmolar hyperglycemic state in a 63 year old female. MUMJ 10(1):39-42, 2013.
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Harper W, Clement M, Goldenberg R, et al. Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada: pharmacologic management of type 2 diabetes. Can J Diabetes 2013;37(suppl 1):S61-S68.
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Brock G, Harper W. Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada: erectile dysfunction. Can J Diabetes 2013;37(suppl 1):S150-S152.
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Natarajan M, Strauss B, Rokoss M, Buller C, Mancini J, Xie C, Sheth T, Goodhard D, Cohen E, Seidelin P, Harper W, Gerstein H. Randomized trial of insulin versus usual care in reducing restenosis after coronary intervention in patients with diabetes. The Stent Restenosis And Metabolism (STREAM) study. Cardiovasc Revasc Med 13(2):95-100, 2012.
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Sherifali D, Greb J, Amirthavasar G, Hunt D, Haynes B, Harper W, et al. Effect of computer-generated tailored feedback on glycemic control In people with diabetes in the community, a randomized controlled trial. Diabetes Care 34(8):1794-8, 2011.
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Baranchuk A, McIntyre WF, Harper W, Morillo CA. Application of the American College of Emergency Physicians (ACEP) recommendations and a risk stratification system (OESIL) for patients with syncope admitted from the Emergency Department. Indian Pacing Electrophysiol J 11(5): 134-44, 2011.
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Graf H, Fast S, Pacini F, Leung A, Vaisman M, Reiners C, Wemeau J, Huysmans, Harper W, et al. Modified-release recombinant human TSH (MRrhTSH) augments the effect of 131I therapy in benign multinodular goiter: results from a multicentre international, randomized, placebo-controlled study. Journal of Clinical Endocrinology & Metabolism 96: 1368-76, 2011.
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Forbes S, Stephen W, Harper W, Loeb M, Smith R, Christoffersen E, McLean R. Implementation of evidence-based practices for surgical site infection prophylaxis: result of a pre- and postintervention study. J Am Coll Surg 207(3):336-41, 2008.
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Harper W, Hanna A, et al. Pharmacologic Management of Type 2 Diabetes. Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada. Canadian Journal of Diabetes 32(suppl1): S53-61, 2008.
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Brock G, Bebb R, Harper W. Erectile Dysfunction. Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada. Canadian Journal of Diabetes 32(suppl1): S147-149, 2008.
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Adams J, Barnard M, Yusta B, Harper W, Drucker D. Glucagon-like peptide-2 does not modify growth or survival of murine or human intestinal tumor cells. Cancer Research 68(19):7897-904, 2008.
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Lau A, Harper W. Thiazolidinediones and their effect on bone metabolism: A Review. Canadian Journal of Diabetes 31(4):378-383, 2007.
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Leonard B, Morris A, Harper W, Rutherford C, Main C. Capnocytophaga Species: Clinical Presentation and Diagnostic Dilemmas. American Journal of Clinical Pathology 127:311, 2007.
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Baranchuk A, Hiralal R, Harper W, Healey J, Connolly SJ, Morillo CA. Application of the American College of Emergency Physicians (ACEP) recommendations and a risk stratification score (OESIL) for patients with syncope admitted in internal medicine service. Europace 7(s3): S6-7. 2005.
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Hiralal R, Harper WL. Appropriate use and Diagnostic Utility of Echocardiography in the Evaluation of Syncope at McMaster University Teaching Hospital. Clin Invest Med 28(5): 283-294, 2005.
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Harper W. Atypical antipsychotic drugs and diabetes mellitus. Connections 2(4): 1-3, 2005.
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Harper W. Recombinant human thyrotropin: treatment of multinodular goitre. Thyroid Canada 10: 14-16, 2005.
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Porter PJ, Willinsky RA, Harper W, Wallace MC. Cerebral cavernous malformations: natural history and prognosis after clinical deterioration with or without hemorrhage. Journal of Neurosurgery 87(2):190-7, 1997.
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Willinsky R, Harper W, Wallace MC, Kucharczyk W, Montanera W, Mikulis D, Ter Brugge K. Follow-up MR of Intracranial Cavernomas, The Relationship between Hemorrhagic Events and Morphology. Interventional Neuroradiology 2: 127-135, 1996.
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Sutherland HJ, Carlin K, Harper W, Martin LJ, Greenberg CV, Till JE, Boyd NF. A study of diet and breast cancer prevention in Canada: why healthy women participate in controlled trials. Cancer Causes & Control 4(6): 521-8, 1993.
Editorial Letters
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Harper W. Case Study Correction. Lab Medicine 35(11): 699, 2004.
Not Peer-Reviewed Publications
Journal Articles
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Frolic A, Harper W, Dees M. Expanded rights to medical assistance in dying are pointless without better support for MAID providers. CBC News Opinion: https://www.cbc.ca/news/opinion/opinion-assisted-dying-maid-legislation-medical-providers-1.5459942. Feb 23, 2020.
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Harper W. Diabetes drugs: What’s safe for the heart? The Medical Post, CanadianHealthcareNetwork.ca. Page 1, 32. October 22, 2013.
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Harper W. Weight loss and diabetes. Knowing Diabetes 11(4):1, 2011
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Harper W. Using A1C to diagnose diabetes. Knowing Diabetes 11(3):3, 2010.
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Harper S, Harper W. Self-monitoring of blood glucose. Knowing Diabetes 9(3):3, 2008.
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Harper W. Preventing dental problems. Knowing Diabetes 9(2):2, 2008.
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Harper W. At what point does a person with diabetes start losing feeling in their feet so they will not feel a cut or scratch there? Knowing Diabetes 9(2):4, 2008.
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Harper W. Oral glucose tolerance test. Knowing Diabetes 9(1):2, 2008.
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Harper W. Celiac disease. Knowing Diabetes 9(1):3, 2008.
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Harper W. Focus on thiazolidinediones and cardiovascular disease. Knowing Diabetes 8(4):1, 2007.
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Harper W. Preventing type 1 diabetes mellitus. Knowing Diabetes 8(1):3, 2007.
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Harper W. Predicting risk of heart disease in people with diabetes. Knowing Diabetes 8(2-3):3, 2007.
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Harper W. Does Avandia increase the risk of having a heart attack or dying from heart disease? Knowing Diabetes 8(2-3):4, 2007.
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Harper W. Emerging Incretin-based Therapies for Type 2 Diabetes. The Diabetes Communicator September/October: 4-5, 2007.
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Harper W. Why has my diabetes improved after my heart bypass operation? Knowing diabetes 7(4): 4, 2006
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Harper W. IFG vs. IGT. Knowing Diabetes 7(3):2, 2006.
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Harper W. Why are NSAIDs harmful to the kidneys? Knowing Diabetes 7(3):4, 2006
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Harper W. Do steroids like prednisone affect my diabetes? Knowing Diabetes 7(2):4, 2006.
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Harper W. Focus on TZD Insulin Sensitizer Medications. Knowing Diabetes 7(1): 1, 2006.
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Harper W. Which is the more serious-hypoglycemia or hyperglycemia? Knowing Diabetes 6(4): 4, 2006.
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Harper W. Worth a Shot? Insulin therapy, the primary treatment for people with type 1 diabetes may also benefit people with type 2 diabetes. The Health Journal 10.2: 48, 2006.
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Harper W. What do I do about my diabetes medications if I am going for surgery? Knowing Diabetes 6(4): 4, 2005.
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Harper W. Is it OK to take insulin after you eat instead of before? Knowing Diabetes 6(3): 4, 2005.
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Harper W. Insulin Antibodies. Knowing Diabetes 6(3): 2, 2005.
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Harper W. Does changing from animal to human insulin cause hypoglycemia? Knowing Diabetes 6(2): 4, 2005.
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Harper W. How to improve communication with your doctor. Knowing Diabetes 6(1): 4, 2005.
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Harper W. What is meant by safe lower CDA blood sugar targets? Knowing Diabetes 5(4): 4, 2004.
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Harper W. Future Treatment of Diabetes with GLP-1. Knowing Diabetes 5(4): 1, 2004.
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Harper W. Physical Activity and Diabetes. Knowing Diabetes 5(3): 1, 2004.
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Harper W. Erectile Dysfunction. Knowing Diabetes 5(2): 3, 2004.
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Harper W. Different Ways to Treat Type 2 Diabetes. Knowing Diabetes 5(2): 1, 2004.
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Harper W. Preventing Diabetes with Coffee? Knowing Diabetes 5(1): 3, 2004.
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Harper W. Is the D-TRON insulin pump obsolete? Knowing Diabetes 4(4): 4, 2003.
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Harper W. 2003 CDA Diabetes Guidelines. Knowing Diabetes 4(4): 1, 2003.
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Harper W. Do all treatments for diabetes cause weight gain? Knowing Diabetes 4(3): 4, 2003.
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Harper W. Preventing dental problems in diabetes. Knowing Diabetes 4(2): 2, 2003.
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Harper W. What’s new in insulin therapy? Knowing Diabetes 3(4): 1, 2002.
Contribution to Books
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Tucker WS, Harper W, Kaibara T (1996). Neurosurgery. Chapter in Arnold P (Editor), 1996 MCCQE Study Guide (pages 1-32). Toronto Notes for Med Students.
Presentations at Meetings
Invited
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Bernstein D, Harper W, Poliakoff M. Antisemitism and Extremism in Education. “Woke” Antisemitism – What is is. How to Fight it. September 22, 2024. Prosserman Jewish Community Center, Toronto ON.
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Harper W. Hypothyroidism: Evaluation, Management and Monitoring. 12th Annual Day in Endocrinology for Primary Care Providers. Canadian Endocrine Update. September 20, 2024.
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Hartwick M, Cameron L, Harper W, Whittingham H, Frolic A. Organ Donation & MAiD in Hamilton. Greater Hamilton Health Network Grand Rounds, April 23, 2024.
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Yousuf H, Oczkowski S, Harper W, Frolic A. Triage-Ed: Lessons Learned from Educating Clinicians on Pandemic Critical Care Triage Protocols. Joint Centre for Bioethics Virtual Seminar Series, University of Toronto, March 2, 2022.
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Harper W. Adrenal insufficiency – how to evaluate and treat. 9th Annual Day In Endocrinology for Primary Care Providers (CEU). October 22, 2021. Virtual CPD, Canada.
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Downie J, Green S, Harper W, Viens P, Plewes L. Bill C-7: What does it mean for assessors and providers? CAMAP Spring 2021 Symposium Webinar. March 31, 2021
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Harper W. Medical assistance in dying and dementia. 10th Annual Geriatrics Update. November 18, 2020. Virtual Conference, Geriatrics Division, Department of Medicine, McMaster University, Hamilton Canada.
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Harper W. Diabetes and COVID19. 2020 Evidence-Based Management of the Diabetes Epidemic – Virtual CPD Conference. November 4, 2020. McMaster University, Hamilton Canada.
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Harper W. Hyperthyroidism – how to evaluate and treat. 8th Annual Day in Endocrinology. Oct 9, 2020. Virtual Conference, Canadian Endocrine Update, McMaster University, Hamilton Canada.
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Chkaroubo A, Harper W. Medical Assistance in Dying. 10th Annual Geriatric Training Program. October 8, 2020. Virtual Conference, Regional Geriatric Program, McMaster University, Hamilton Canada.
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Harper W. Why am I urinating so much, Diabetes Insipidus? 8th Annual Canadian Endocrine Review (CERC). April 26, 2019. London, Canada.
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Harper W. Examination of the foot in a patient with Diabetes. Workshop at Day in Endocrinology for Primary Care Providers by CEU. Liuna Station, April 11, 2019. Hamilton, Canada.
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Harper W. Update on MAiD: What have we learned? 11th Annual McMaster University Review Course in Internal Medicine. March 29, 2019. Hamilton, Canada.
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Harper W. Cases 2: Choosing the Next Glucose Lowering Drug. 2017 Evidence-Based Management of the Diabetes Epidemic. Liuna Station. November 15, 2017. Hamilton, Canada.
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Harper W. How low do I go, Inpatient DM management? 6th Annual Canadian Endocrine Review (CERC). April 22, 2017. London, Canada.
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Harper W. Adrenal and Pituitary Testing. 9th Annual McMaster University Review Course In Internal Medicine. March 30, 2017. Hamilton, Canada.
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Shah R, Aziz T, Yakubovich N, Harper W, Punthakee Z. Metasttic differentiation of a serotonin to an insulin-secreting neuroendocrine tumor. Resident Clinical Vignettes Presentation. CDA/CSEM Professional Conference and Annual Meeting. October 23, 2014. Winnipeg, Canada.
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Orr C, Harper W. Diagnosis and management challenges with multifocal pheochromocytoma. International Congress of Endocrinology & Endocrine Society 2014 (96th annual meeting & expo). June 22, 2014. Chicago, USA.
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Harper W. MTP Session 2 – Thyroid Function Tests Interpretation. Day in Endocrinology for Primary Care Providers by Canadian Endocrine Update. May 2, 2014. Hamilton, Canada.
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Harper W. Inpatient diabetes mellitus. 3rd Annual Canadian Endocrine Review Course. April 12, 2014. McMaster University, Hamilton, Canada.
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Harper W. Review of Diagnosis and Treatment of Adrenal Insufficiency. 6th Annual McMaster University Review Course in Internal Medicine. April 3, 2014. Hamilton, Canada.
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Harper W. Lowering glucose: individualizing targets and treatment. Primary Care Providers Symposium. 16th Annual CDA/CSEM Professional Conference and Annual Meeting. October 19, 2013. Montreal, Quebec.
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Harper W. The Changing Face of Diabetes. 96th Annual Clinical Day of The Hamilton Academy of Medicine. January 30, 2013. Hamilton, Ontario.
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Azharuddin M, Harper W, Al-Owami S. Pituitary metastases and pituitary insufficiency exceptionally rare presentation of most common thyroid cancer. 15th Annual Canadian Diabetes Association/Canadian Society of Endocrinology and Metabolism Professional Conference and Meeting, Oral abstract 7, October 11, 2012. Vancouver, British Columbia.
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Inman A, Ostro J, Harper W. Utility of the Burch and Wartofsky scoring system for diagnosing thyroid storm and predicting adverse outcomes in a contemporary cohort of patients with thryotoxicosis. 23rd Annual Resident Research Day. Faculty of Health Sciences, Department of Medicine, McMaster University, May 16, 2012. Hamilton, Ontario.
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Harper W. Diabetes Insipidus. 1st Annual Canadian Endocrine Review Course. April 28, 2012. McMaster University, Hamilton, Canada.
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Harper W. Meet the Professor 2: Abnormal Thyroid Function Tests. 7th Annual Canadian Endocrine Update. April 28, 2012. McMaster University and University of Western Ontario, Hamilton, Canada.
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Harper W. New drugs for diabetic patients. 4th Annual McMaster University Review Course in Internal Medicine. March 30, 2012. Hamilton, Canada.
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Harper W. Emerging Trends in Diabetes Management. 5th Annual Diabetes Update. November 18, 2011. University of Manitoba, Winnipeg, Canada.
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Gerstein H, Harper W. Debate: Metformin’s not enough – What Next? Basal Insulin vs. Something Else. 2011 Evidence Based Management of the Diabetes Epidemic. November 16, 2001. Hamilton, Canada.
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Coons M, Hall P, Rodin G, Harper W. The Influence of Diabetes-Related Worry on Health-Related Quality of Life in Type 1 diabetes mellitus. 45th Annual Convention of the Association for Behavioral and Cognitive Therapies. November 10-13, 2011. Toronto, Canada.
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Ostro J, Inman A, Mohamed N, Harper W. Utility of the Burch and Wartofsky scoring system for diagnosing thyroid storm and predicting adverse outcomes in a contemporary cohort of patients with thryotoxicosis. 81st Annual Meeting of the American Thyroid Association. October 26-30, 2011. Indian Wells, CA.
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Ostro J, Inman A, Mohamed N, Harper W. Utility of the Burch and Wartofsky scoring system for diagnosing thyroid storm and predicting adverse outcomes in a contemporary cohort of patients with thryotoxicosis. 14th Annual Canadian Diabetes Association/Canadian Society of Endocrinology and Metabolism Professional Conference and Meeting, Abstract 261. October 26-29, 2011. Toronto, Ontario.
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Harper W. Conflict Management. McMaster University Internal Medicine Medicine SMR Day Retreat. July 12, 2011. Ancaster, Ontario.
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Harper W. Conflict Management. McMaster University Internal Medicine Medicine SMR Day Retreat. July 6, 2010. Ancaster, Ontario.
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Coons MJ, Hall PA, Rodin G, Harper W. The nature of diabetes-related worry behavior in Type 1 diabetes mellitus (T1DM). 44th Annual Convention of the Association for Behavioral and Cognitive Therapies. November 2010. San Francisco, CA.
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Sarkar U, Harper W. Adherence to recent American Thyroid Association Taskforce Guidelines to manage differentiated thyroid cancer after total or near-total thyroidectomy. 21st Annual Resident Research Day. Faculty of Health Sciences, Department of Medicine, McMaster University, May 26, 2010. Hamilton, Ontario.
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Harper W. Meet the Professor 2: Thyroid Cancer – RAI Controversies. Canadian Endocrine Update. April 9, 2010. McMaster University and University of Western Ontario, Hamilton, Canada.
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Harper W. New Drugs for Diabetes. 2nd McMaster Review Course in Internal Medicine, McMaster University. March 26, 2010. Hamilton, Ontario
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Harper W. What about steroids and insulin in the ICU? McMaster Review Course in Internal Medicine, McMaster University. April 3, 2009. Hamilton, Ontario.
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Harper W. Diabetes, New Therapies in the midst of a pandemic. 52nd Annual Ontario Anesthesia Meeting, Ontario Medical Association, Section of Anesthesiology. September 28, 2007. Niagara Falls, Ontario.
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Amer R, Morris A, Woo T, Davis C, Mulji A, Harper W. A Case of Possible Propylthiouracil (PTU)-Induced P-ANCA Vasculitis Resulting in Pleuropericarditis. 17th Annual Resident Research Day. Winner 1st Prize for Case Reports. Faculty of Health Sciences, Department of Medicine, McMaster University, May 17, 2006. Hamilton, Ontario.
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Kogan E, Harper W. TSH-Producing Pituitary Adenoma in A Young Man. 17th Annual Resident Research Day. Faculty of Health Sciences, Department of Medicine, McMaster University, May 17, 2006. Hamilton, Ontario.
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Leonard BJN, Morris A, Harper W, Rutherford C, Main C. Bacterial Meningitis after Transsphenoidal Surgery in a Non-neutropenic Patient with Capnocytophaga sputigena: A Case Report. Association of Medical Microbiology and Infections Disease Canada – Canadian Association for Clinical Microbiology and Infectious Diseases Annual Conference. March 16, 2006. Victoria, British Columbia.
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Khera V, Harper W. Inpatient Management of Diabetes. Oral Presentation. 16th Annual Resident Research Day. Faculty of Health Sciences, Department of Medicine, McMaster University. May 18, 2005. Hamilton, Ontario.
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Hiralal R, Morillo C, Harper W. Application of the American College of Emergency Physicians (ACEP) recommendations and a risk stratification system (OESIL) for patients with syncope admitted to the Internal Medicine Service. Oral Presentation. 16th Annual Resident Research Day. Faculty of Health Sciences, Department of Medicine, McMaster University. May 18, 2005. Hamilton, Ontario.
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O’Shea T, Harper W. A 49-Year-Old Male with a Germ Cell Tumour and Insulinoma. Case Report Poster Presentation. 16th Annual Resident Research Day. Faculty of Health Sciences, Department of Medicine, McMaster University. May 18, 2005. Hamilton, Ontario.
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Baranchuk A, Hiralal R, Harper WL, Connolly S, Morillo CA. Application of the American College of Emergency Physicians (ACEP) recommendations and a risk stratification system (OESIL) for patients with syncope admitted to the Internal Medicine Service. Heart Rhythm Society 26th Annual Scientific Section. May 4-7, 2005. New Orleans, LA, USA.
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Hiralal R, Harper WL. Appropriate use and Diagnostic Utility of Echocardiography is the Evaluation of Syncope at a McMaster University Teaching Hospital. Heart and Stroke Clinical Update 2004. December 9-11, 2004. Toronto, Ontario.
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Hiralal R, Harper W. Appropriate Use and Diagnostic Utility of Echocardiography in the Evaluation of Syncope at a McMaster University Teaching Hospital. Scientific Poster Presentation. 15th Annual Residents’ Research Day in Medicine. Faculty of Health Sciences, Department of Medicine, McMaster University. May 12, 2004. Hamilton, Ontario.
Contributed
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Harper W. Equity and Game Theory Strategies to promote Diversity and Inclusion in Academic Health Science Centres. Citywide Endocrine Rounds, Division of Endocrinology, Department of Medicine, McMaster University, Virtual Zoom. Dec 21, 2021.
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Harper W. MAiD for Hematology Patients. Hematology & Thromboembolism Grand Rounds. McMaster (Virtual), Hamilton, Canada November 12, 2021.
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Frolic A, Harper W, Demers C. End-of-Life Care for Cardiology Patients. Cardiology Regional Grand Rounds. Hamilton Health Science, Hamilton, Canada June 15, 2021.
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Anand S, Harper W. Bridging the Gap: Part 6 – Changing the way we hire, promote and lead: Disrupting systemic “isms” in academic medicine. Pediatric Grand Rounds. McMaster, Hamilton, Canada. June 3, 2021.
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Alaimi A, Lucas G, Lee W, Harper W. Navigating Medical Assistance in Dying and Bill C-7. HHS Medical Grand Rounds. Hamilton, Canada. April 8, 2021.
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Andrea Frolic, Harper W, Kathryn Morrison. Medical Assistance in Dying: Current Practice And Changes under Bill C-7. Virtual HHS Ethics Grand Rounds. McMaster University Medical Centre, Hamilton Canada, March 24, 2021.
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Harper W, Massarella C. Transgender Care. Virtual Chair’s Grand Rounds, McMaster University, Dept. of Medicine, Hamilton Canada, Feb 4, 2021.
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Harper W. COVID-19 and Diabetes. Virtual Citywide Endocrine Rounds, Division of Endocrinology, Dept. of Medicine, McMaster University, Hamilton Health Sciences. November 17, 2020.
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Harper W, Andrea Frolic, Simon Oczkowski. Novel Coronavirus Global Pandemic. HHS Ethics Grand Rounds. McMaster University Medical Centre, Hamilton Canada, March 11, 2020.
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Harper W, Marta Simpson. Update on Medical Assistance in Dying. HHS Ethics Grand Rounds. Sept 11, 2019. MUMC, Hamilton Canada.
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Anand S., Harper W. Is there really a Gender Gap in the Department of Medicine and Academic Medicine Writ Large? Medical Grand Rounds, Hamilton Health Sciences, April 11, 2019.
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Harper W. Cardiovascular Risk Reduction with Antihyperglycemics in Type 2 Diabetes. Medical Grand Rounds, Hamilton Health Sciences, Nov 30, 2017.
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Harper W. Cardiovascular Risk Reduction with Antihyperglycemics in Type 2 Diabetes. Chairs Grand Rounds, St. Joseph’s Healthcare, April 6, 2017.
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Harper W. Pharmacotherapy of Type 2 Diabetes. Citywide Endocrine Rounds, Division of Endocrinology, Dept. of Medicine, McMaster University, St. Joseph’s Healthcare. Oct 21, 2014.
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Harper W. Canadian Diabetes Association 2013 Clinical Practice Guidelines Update. Department of Family Medicine Grand Rounds, St. Joseph’s Healthcare, April 19, 2013.
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Harper W. Thyroid Disorders and Hyperparathyroidism. ENT Grand Rounds, Division of ENT, Department of Surgery, McMaster University, April 17, 2013.
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Harper W. DKA: Standardization of Care. Citywide Endocrine Rounds, Division of Endocrinology, Department of Medicine, McMaster University, St. Joseph’s Healthcare. Sept 18, 2012.
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Harper W. Severe Hyperthyroidism (Someone told me long ago, there’s a calm before the storm). Medical Grand Rounds, Hamilton Health Sciences. May 31, 2012. Hamilton, ON.
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Bednar D, Harper W. The back-pain disabled patient; pitfalls and what not to miss. Medical Grand Rounds, Hamilton Health Sciences. April 26, 2012. Hamilton, ON.
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Harper W. Management of Thyroid Nodular Disorders. Citywide Endocrine Rounds, Division of Endocrinology, Department of Medicine, McMaster University, Hamilton Health Science. January 20, 2009, Hamilton, ON.
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Harper W. Optimizing the Treatment of T2DM, Novel Therapies: DPP-IV inhibitors. Family Practice Rounds, Hamilton Health Sciences. June 9, 2008. Hamilton, ON.
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Harper W. Type 2 Diabetes Mellitus: Optimizing Glycemia. Nephrology Grand Rounds, St. Joseph’s Hospital. May 12, 2006. Hamilton ON.
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Harper W. Sodium Disorders. Medical Grand Rounds, Hamilton Health Sciences. April 20, 2006. Hamilton ON.
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Harper W. Harvey Cushing and his Syndrome. Pituitary Disorders Conference. Division of Neurosurgery, Department of Surgery, McMaster University. Hamilton Health Sciences. Dec 2, 2005. Hamilton ON.
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Harper W. Inpatient Management of Diabetes Mellitus and Hyperglycemia. Citywide Endocrine Rounds, Division of Endocrinology, Department of Medicine, McMaster University. Hamilton Health Sciences. Nov 15, 2005. Hamilton ON.
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Harper W. Non-Diabetic Hypoglycemia. Family Medicine Grand Rounds, St. Joseph’s Hospital. May 20, 2005. Hamilton ON.
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Harper W. Inpatient Management of Diabetes Mellitus and Hyperglycemia. Chairs Grand Rounds, Department of Medicine, McMaster University. St. Joseph’s Hospital. April 6, 2005. Hamilton ON.
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Harper W. Trauma: Management of Diabetes Mellitus & Stress Hyperglycemia. Trauma Rounds, Hamilton Health Sciences. Feb 22, 2005. Hamilton ON.
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Harper W. Type 2 Diabetes mellitus: Treating to Targets? Family Medicine Grand Rounds, St. Joseph’s Hospital. May 21, 2004. Hamilton ON.
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Harper W. Non-Diabetic Hypoglycemia. Medical Grand Rounds, Hamilton Health Sciences. May 14, 2004. Hamilton ON.
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Harper W. Diabetes mellitus & Cardiovascular Disease. Cardiology Grand Rounds, Division of Cardiology, Department of Medicine, McMaster University. Hamilton Health Sciences. May 11, 2004. Hamilton ON.
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Harper W. Diabetes and Schizophrenia. Grand Rounds, Department of Psychiatry, McMaster University. Hamilton Health Sciences. Dec 17, 2003. Hamilton ON.
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Harper W. Diabetes and Schizophrenia. Citywide Endocrine Rounds, Division of Endocrinology, Department of Medicine, McMaster University. Hamilton Health Sciences. Dec 16, 2003. Hamilton ON.
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Harper W. Diagnosis of Thyroid Disorders. Family Medicine Grand Rounds, Hamilton Health Sciences. Dec 9, 2003. Hamilton ON.
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Harper W. Extreme Endocrinology. Medical Grand Rounds, Hamilton Health Sciences. Jan 24, 2003. Hamilton ON.
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Harper W. Extreme Endocrinology. Citywide Endocrine Rounds, Division of Endocrinology, Department of Medicine. Hamilton Health Sciences. Jan 21, 2003. Hamilton ON.
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Harper W. Extreme Endocrinology. Chair’s Grand Rounds, Department of Medicine, McMaster University. St. Joseph’s Hospital. Jan 8, 2003. Hamilton ON.
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Harper W. A 64 y.o. Female with Hypercalcemia & Renal Failure. Chair’s Grand Rounds, Department of Medicine, McMaster University. Hamilton Health Sciences. November 21, 2002. Hamilton ON.
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Harper W. Cushing’s Syndrome. Neurology & Neurosurgery Grand Rounds, Hamilton Health Sciences. June 13, 2002. Hamilton ON.
Administrative Responsibilities
Clinical Administration
Member, Executive Committee, McMaster Medicine Alternative Funding Plan (AFP). March 2019 – 2021.
Physician Lead, Assisted Dying Resource and Assessment Service (ADRAS) for Medical Assistance in Dying (MAiD) assessment and provision, Dept. of Complex Care, Aging & Palliative Care, Hamilton Health Sciences. Sep 2018 – Aug 2021.
Member, Medication Safety Committee, Hamilton Health Sciences.
April 2013 – 2015.
Chief of Medicine, Hamilton General Hospital. March 2013 – July 2015.
Endocrinologist Team Member, Ontario Program for Radionuclide Therapy for Neuroendocrine Tumor Patients (Consortium: Juravinski Cancer Centre and Hamilton Health Sciences, Odette Cancer Centre and Sunnybrook Health Science Centre, Princess Margaret Hospital and the University Health Network). September 2011 – Present.
Endocrinologist Lead, Diabetes Regional Coordination Centre, Hamilton Niagara Haldimand Brant Local Health Integration Network. Aug 2010 – Jan 2013.
Member, Financial Management Committee, McMaster Medicine Alternative Funding Plan (AFP). Jan 2009 – Sept 2018.
Member, Adult Inpatient Insulin Protocol Working Group. Cardiovascular Program, Hamilton Health Sciences. Feb 2005 – 2007.
Chair, Surgical Site Infection Glucose-Control Group. Department of Surgery and Anesthesia, Hamilton Health Sciences. Jan 2005 – 2008.
Member, Surgical Site Infection Steering Group. Department of Surgery and Anesthesia, Hamilton Health Sciences. Dec 2004 – 2008.
Member, Death Review Committee. Department of Medicine, Hamilton Health Sciences. Sept 2003 – April 2012.
Educational Administration
Division Director, Endocrinology & Metabolism, Department of Medicine, Faculty Health Sciences, McMaster University. 2019 – 2024.
DAvNE Consultant to the Associate Chair Equity and Diversity, Department of Medicine, Faculty of Health Sciences, McMaster University. 2019 – Oct 7, 2023.
CTU Director, Hamilton General Site. Postgraduate Internal Medicine Program, McMaster University. 2007 – 2012.
Associate CTU Director, Hamilton General Site. Postgraduate Internal Medicine Program, McMaster University. 2005 – 2007.
Faculty Advisor for Endocrinology Academic Half-Days. Postgraduate Internal Medicine Program, McMaster University. 2005 – 2015.
Member, Educator’s Collegium. Programs for Faculty Development and Educational Research, McMaster University. 2005 – 2006.
Member, General Internal Medicine Training Committee. Postgraduate Internal Medicine Program, McMaster University. 2005 – 2012.
Director, Medical Foundations 2. Michael G. DeGroote School of Medicine, McMaster University. 2004 – 2011.
SubUnit Planner, Endocrinolgy, Medical Foundations 2. Michael G. DeGroote School of Medicine, McMaster University. 2004 – 2011.
SubUnit Planner, Endocrinology, Unit 3. Michael G. DeGroote School of Medicine, McMaster University. 2003 – 2005.
Endocrinology Site-Coordinator, Hamilton Health Sciences. Postgraduate Internal Medicine Program, McMaster University. 2002 – 2007.
Clinical Service Responsibilities
ADRAS, Hamilton Health Sciences. MAiD assessment and provision.
August 2017 – Present
Inpatient Endocrine Consultations, Hamilton General Site, Hamilton Health Sciences. 48 patients/year (approx). 2002 – Present
Internal Medicine CTU Attending, Hamilton General Site, Hamilton Health Sciences. 4 months service/year, 464 patients/year (approx). 2002 – Present
Endocrinology Clinics, Hamilton General Site, Hamilton Health Sciences.
2 clinics/week, 576 patients/year (approx). 2002 – Present
Diabetes Clinics, McMaster University Medical Centre, Hamilton Health Sciences. 2 clinics/week, 576 patients/year (approx). 2002 – Present
Volunteer Activities
Board Treasurer, Hamilton Interval House, Women & Children Emergency Shelter and Support Services. July 2021 - Present
Board Member, Hamilton Interval House, Women & Children Emergency Shelter and Support Services. February 2019 - Present
Trainer, Hamilton Huskies Hockey Minor Bantam (age 13), Qualifications (HCSP Trainer Level 1, Respect in Sport, Gender Identity & Expression). 2018 - 2020